Glycerin 21 vs. Glycerin 22: What’s New?
The Brooks Glycerin line combines luxurious comfort with performance. In this article, we explore the evolution of the Glycerin series—specifically comparing the Glycerin 21 with the new Glycerin 22.
Whether you're a passionate runner or just beginning your fitness journey, understanding the key differences in the latest Glycerin 22 can help you make the best choice for your needs.
The Glycerin Series
The Brooks Glycerin family is renowned for its outstanding cushioning and comfort, making it a top choice for runners and walkers of all levels. Whether you’re an experienced athlete or a beginner who prefers walking, the Glycerin series delivers a premium shock-absorbing experience with cutting-edge technology.
A standout feature of the Glycerin line is the combination of soft and responsive nitrogen-infused cushioning, resulting in a perfectly tuned, seamless running experience. It’s a chance to feel that “run forever” sensation with endless energy in every step.
Whether you’re trying out the latest Glycerin 22 or sticking with the trusted Glycerin 21, you can choose between the classic fit or added support via the GTS (go-to-support) versions. Brooks has also introduced the Glycerin Max, offering a higher stack of DNA Tuned foam and a GlideRoll Rocker for effortless heel-to-toe transitions. With so many options, it’s easy to find the perfect Glycerin based on your needs.
Enjoy the unmatched comfort and performance of the Glycerin series, and elevate your run to new heights. Whether you’re hitting the pavement or going for a long walk, these shoes are made to support every step.
Glycerin 21 vs. Glycerin 22: How They Compare
Choosing the right running shoe means paying attention to the details. The Glycerin 22 is an evolution of the popular Glycerin 21, bringing exciting new enhancements for those seeking the latest in performance tech. Here's how they compare:
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Tuned Cushioning: Both models offer the same drop and midsole height, but the Glycerin 22 features DNA Tuned cushioning—next-generation nitrogen-infused foam with dual-size cell technology. This provides plush landings and explosive toe-offs.
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Upgraded Upper: The Glycerin 22 comes with a redesigned double jacquard engineered mesh upper, offering improved comfort, breathability, and a more adaptive fit.
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Custom Fit Options: Both the Glycerin 21 and 22 are available in standard and GTS versions, featuring Brooks' GuideRails™ technology for added support where needed.
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Smooth Transitions: A wide platform underfoot helps stabilize your stride for smooth heel-to-toe transitions in both models.
Glycerin 21
The Brooks Glycerin 21 was designed for those who value maximum comfort and support. With a plush design, it’s ideal for both experienced runners and beginners.
One standout feature is its DNA LOFT v3 midsole, which delivers an incredibly soft and luxurious feel in every step. It was also the first Glycerin to introduce RoadTack rubber in the outsole. While the Glycerin 21 may still be a perfect fit for you, the Glycerin 22 brings the latest advancements to the table.
Glycerin 22
The latest addition to the Glycerin series, the Glycerin 22, is a premium running shoe built for luxurious comfort, soft landings, and energized toe-offs.
You’ll find the all-new DNA Tuned foam in the Glycerin 22—a nitrogen-infused midsole with dual-size cells, optimized for both plush landings and dynamic responsiveness. (Fun fact: Glycerin Max was the first to debut DNA Tuned!) It also offers a soft, secure fit thanks to a newly designed double-layer engineered mesh upper.
Whether you go with the classic fit or GTS for added support, the Glycerin 22 is built to help you unlock that “run forever” feeling.
Is It Time to Upgrade to the Glycerin 22?
Both the Glycerin 21 and 22 are excellent choices—whether you're a runner or an avid walker looking for great cushioning and support.
The Glycerin 21 features the DNA LOFT v3 midsole and a traditional knit upper, while the Glycerin 22 has been upgraded with the new DNA Tuned foam and a more breathable, flexible double jacquard mesh upper.
Ultimately, finding the right fit depends on your personal preferences. Whether you try the newest Glycerin 22 or want to explore other popular Brooks models like the Adrenaline GTS or the Ghost, we’ve got you covered.
Still need help deciding? Visit your local running store for a fitting and expert advice.
